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IL6 — P2RX7

Text-mined interactions from Literome

Solini et al., Arterioscler Thromb Vasc Biol 2004 (Diabetes Mellitus, Type 2...) : We found that fibroblasts from diabetic subjects are characterized by enhanced P2X7 mediated responses as indicated by increased shape changes, microvesiculation, enhanced fibronectin and interleukin 6 secretion, and accelerated apoptosis
Solini et al., Endocrinology 2008 (Carcinoma, Papillary...) : Ca ( 2+ ) increase was attenuated and release of IL-6 was fully blocked by P2X(7)R inhibitors
Caporali et al., J Mol Med (Berl) 2008 (Arthritis, Rheumatoid...) : Thus, we investigated the presence of P2 receptors in human type B synoviocytes from rheumatoid joints, also evaluating whether the P2X7 receptor is involved in IL-6 release
Friedle et al., Glia 2011 (Inflammation) : Moreover, using RNAi, we demonstrate that Egr factors and P2X7 receptors are necessary for BzATP mediated attenuation of iNOS, and stimulation of TNF-a and IL-6 gene expression
Jalilian et al., Vet Immunol Immunopathol 2012 : Activation of the damage associated molecular pattern receptor P2X7 induces interleukin-1ß release from canine monocytes
Xu et al., Brain Res Bull 2013 (MAP Kinase Signaling System) : Therefore, high concentrations of FFAs increased the expression of P2X7 in PC12 cells via activation of p38 mitogen activated protein kinase ( MAPK ) signaling pathway, which contributed to P2X7 mediated IL-6 release from PC12 cells