Gene interactions and pathways from curated databases and text-mining

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PGP — PTGS2

Text-mined interactions from Literome

Lee et al., Res Vet Sci 2007 (Carcinoma, Transitional Cell...) : These results suggest that P-gp expression is induced by overexpression of COX-2 in canine patients with TCC
Holtman et al., Epilepsy Res 2010 (Chronic Disease...) : Recent studies show that cox-2 can regulate expression of P-glycoprotein (P-gp) during epileptogenesis and epilepsy
Gu et al., Asian Pac J Cancer Prev 2012 (Adenocarcinoma...) : COX-2 may induce the expression of P-gp in SGC7901 cell line via the NF-kappa B pathway with pacliaxel stimulation
Choi et al., Eur J Pharm Sci 2013 (Edema) : Our data indicate that the decrease of P-gp expression is caused by the decreased expression of COX-2 through the MAPK/AP-1 pathway