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CRP — GP6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Bobe et al., Blood 2001
(Agammaglobulinemia) :
Activation of the collagen receptor
glycoprotein VI (GPVI) by a
collagen related peptide (CRP) induces stimulation of platelets and megakaryocytes through the phosphatidylinositol (PI) 3-kinase dependent pathway leading to activation of Bruton tyrosine kinase (Btk) and phospholipase Cgamma2 ( PLCgamma2 )
Merino et al., Am J Cardiol 2004
(Coronary Disease) :
It was found that
glycoprotein IIb/IIIa inhibition significantly
blocked postangioplasty
CRP increases in all patients but blocked IL-6 increases only in patients carrying the -174 GG genotype
Molins et al., Cardiovasc Res 2011
(Thrombosis) :
Platelet aggregation and flow cytometry analysis revealed that monomeric
C-reactive protein significantly
induced platelet aggregation, surface P-selectin and CD63 exposure, and
glycoprotein IIb-IIIa activation, whereas pentameric C-reactive protein was unable to produce any effect