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CXCR4 — IL7
Text-mined interactions from Literome
Llano et al., J Virol 2001
(Acquired Immunodeficiency Syndrome) :
IL-7 induced T-cell proliferation and up-regulated
CXCR4 expression in peripheral blood mononuclear cells in vitro
Pedroza-Martins et al., J Virol 2002
(HIV Infections) :
IL-2 and IL-4 together increased expression of CXCR4 and CCR5 in this population, whereas IL-4 and
IL-7 increased
CXCR4 but not CCR5 expression
Schmitt et al., J Virol 2003
:
This positive
regulation of
CXCR4 by
IL-7 in mature CD4 ( + ) thymocytes correlates with their high capacity to favor X4 virus replication compared with intermediate thymocytes or peripheral blood mononuclear cells