Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — PPP2CA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ratcliffe et al., J Biol Chem 2000 : Although Wnt signaling is thought to occur via regulation of beta-catenin degradation, PP2A-C did not significantly affect beta-catenin stability
Zhang et al., J Biol Chem 2009 : In this study, we show that PP2A regulates beta-catenin phosphorylation and degradation in vivo ... We demonstrate that PP2A is required for Wnt/beta-catenin signaling in Drosophila
Hu et al., PloS one 2009 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : While exerting suppressive effects on BCR-ABL, E2F1, and beta-catenin , IM/BOR and IM/PSI inhibited proteasomal degradation of protein phosphatase 2A (PP2A) , leading to a re-activation of this important negative regulator of BCR-ABL