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CALM2 — GAP43
Pathways - manually collected, often from reviews:
-
NCI Pathway Database N-cadherin signaling events:
CaM (CALM2)
→
GAP43 (GAP43)
(modification, collaborate)
Meiri et al., J Neurosci 1998*
Evidence: assay, other species
-
NCI Pathway Database N-cadherin signaling events:
CaM (CALM2)
→
GAP43/CaM complex (GAP43-CALM2)
(modification, collaborate)
Meiri et al., J Neurosci 1998*
Evidence: assay, other species
-
NCI Pathway Database N-cadherin signaling events:
GAP43 (GAP43)
→
GAP43/CaM complex (GAP43-CALM2)
(modification, collaborate)
Meiri et al., J Neurosci 1998*
Evidence: assay, other species
-
NCI Pathway Database N-cadherin signaling events:
GAP43/CaM complex (GAP43-CALM2)
→
None
(modification, collaborate)
Meiri et al., J Neurosci 1998*
Evidence: assay, other species
Text-mined interactions from Literome
Zakharov et al., Biochemistry (Mosc) 2005
:
Our results indicate that m-calpain mediated
GAP-43 proteolysis
regulated by PKC and
calmodulin is of physiological relevance, particularly in axonal growth cone guidance
Zakharov et al., J Neurochem 2007
:
M-calpain mediated cleavage of
GAP-43 near Ser41 is negatively
regulated by protein kinase C,
calmodulin and calpain inhibiting fragment GAP-43-3
Gerendasy et al., Mol Neurobiol 1997
(Congenital Hypothyroidism...) :
We propose a model wherein RC3 and
GAP-43 regulate calmodulin availability in dendritic spines and axons, respectively, and
calmodulin regulates their ability to amplify the mobilization of Ca2+ in response to metabotropic glutamate receptor stimulation