Gene interactions and pathways from curated databases and text-mining

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HDAC3 — TCF7

Text-mined interactions from Literome

Mahlknecht et al., J Immunol 2004 : Results further indicated that HDAC3 decreases the MAPK11 phosphorylation state and inhibits the activity of the MAPK11 dependent transcription factor , activating transcription factor-2 ( ATF-2 )
Chuang et al., Nucleic Acids Res 2006 : Histone deacetylase 3 binds to and regulates the GCMa transcription factor
Matteucci et al., Mol Cancer Res 2007 (Breast Neoplasms...) : Thus, the CXCR4 induction by HGF in MCF-7 cells required NF-kappaB and Ets1 activations, downstream of phosphoinositide-3-kinase/Akt, whereas in HGF treated MDA-MB231 cells, HDAC3 activation via c-Src probably caused a reduction of transcription factor activities, such as that of NF-kappaB