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EGFR — LILRB1
Text-mined interactions from Literome
Kefas et al., Cancer Res 2008
(Brain Neoplasms...) :
miR-7 potently
suppressed epidermal growth factor receptor expression, and furthermore it independently inhibited the Akt pathway via targeting upstream regulators
Duex et al., J Biol Chem 2011
(Neoplasms) :
Given earlier evidence of
EGFR regulation by the microRNA
miR-7 , we assessed whether miR-7 mediates Usp18 siRNA effects
Lee et al., Radiother Oncol 2011
:
Ectopic overexpression of
miR-7 attenuated
EGFR and Akt expression and radiosensitized SQ20B squamous cell carcinoma of the larynx, MDA-MB-468 breast cancer cells, A549 lung carcinoma cells, and U251 and U87 malignant glioma cells
Kalinowski et al., PloS one 2012
(Head and Neck Neoplasms) :
Regulation of
epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by
miR-7
Masuda et al., Journal of translational medicine 2012
(Breast Neoplasms) :
Transfection of
miR-7 significantly
suppressed EGFR mRNA levels in MCF-7 cells
Wang et al., Neoplasma 2013
(Brain Neoplasms...) :
Western blotting analysis was performed, which indicated that
miR-7 directly
inhibited epidermal growth factor receptor (EGFR) and further antagonized the downstream protein kinases including ERK, Akt and Stat3
Chen et al., Evidence-based complementary and alternative medicine : eCAM 2013
:
Our data showed the
miR-7 dependent
EGFR suppression by HBx, supporting an inhibitory role of HBx in the cell growth of HCC