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CALM3 — ITPR3
Pathways - manually collected, often from reviews:
-
KEGG Oocyte meiosis:
ITPR1/ITPR2/ITPR3
→
CALM1/CALM2/CALM3/CALML3/CALML5/CALML6
(enzyme-enzyme, compound)
-
KEGG Long-term potentiation:
CALM1/CALM2/CALM3/CALML3/CALML5/CALML6
→
ITPR1/ITPR2/ITPR3
(protein-protein, compound)
-
KEGG GnRH signaling pathway:
ITPR1/ITPR2/ITPR3
→
CALM1/CALM2/CALM3/CALML3/CALML5/CALML6
(protein-protein, compound)
Text-mined interactions from Literome
Vermassen et al., Biochem Biophys Res Commun 2004
:
Ca ( 2+ ) and
CaM , however, did not
inhibit IP(3)R3 phosphorylation by PKC ... Taken together, these findings show that Ca ( 2+ ) and
CaM differentially
regulate the PKC mediated phosphorylation of IP(3)R1 and
IP(3)R3 and are indicative for a role for the inhibition of IP(3)R1 phosphorylation by Ca ( 2+ ) and CaM in the negative slope of the bell shaped effect of Ca ( 2+ ) on IP ( 3 ) R function
Kasri et al., Biol Res 2004
:
Here we focus on the mechanism by which
CaM regulates the
inositol 1,4,5-trisphosphate receptor ( IP3R )
Miyakawa et al., BMC nephrology 2013
(Calcium Signaling) :
Intracellular Ca2+ buffering with BAPTA,
inositol 1,4,5-trisphosphate receptor ( InsP3R )
inhibition with 2-aminoethoxydiphenyl borate ( 2-APB ) or
Ca2+/Calmodulin dependent kinase inhibition with KN-93 completely abolished ouabain stimulated PC2 translocation to the PM