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BMP4 — WNT5A

Text-mined interactions from Literome

Li et al., Dev Biol 2002 : Absence of WNT5a activity in the mutant lungs leads to increased expression of Fgf-10, Bmp4 , Shh, and its receptor Ptc, raising the possibility that WNT5a, FGF-10, BMP4, and SHH signaling pathways are functionally interactive
Dai et al., Cancer Res 2008 (Neoplasm Metastasis...) : Transfection of C4-2B cells with axin, an inhibitor of canonical Wnt signaling, blocked Wnt3a but not Wnt5a induction of the BMP promoters ... In contrast, Jnk inhibitor I blocked Wnt5a but not Wnt3a induction of the BMP promoters
Olivares-Navarrete et al., Acta Biomater 2011 : Wnt5a , but not Wnt3a, increased MG63 cell differentiation and BMP2 and BMP4 proteins, suggesting Wnt5a promotes osteogenic differentiation through production of BMPs. Effects of exogenous and endogenous Wnt5a were synergistic with surface microstructure, suggesting the response also depends on cell maturation state