◀ Back to TCF15
IRS2 — TCF15
Text-mined interactions from Literome
Yang et al., Mol Biol Cell 2010
:
In contrast, PKR regulates
IRS2 , another major IRS family protein in the liver, at the transcriptional rather than the posttranslational level, and this effect is
mediated by the
transcription factor , FoxO1, which has been previously shown to be regulated by insulin and plays a significant role in glucose homeostasis and energy metabolism
Liu et al., PloS one 2012
(Diabetes Mellitus, Type 2) :
IRS-2 expression is
stimulated by the
transcription factor cAMP response element binding protein ( CREB ) and we recently demonstrated that Ca ( 2+ ) /calmodulin dependent kinase 4 (CaMK4) is upstream of CREB activation in ß-cells