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BMP2 — EDN1
Text-mined interactions from Literome
Nett et al., Life Sci 2006
(Diabetes Mellitus, Experimental...) :
Transcriptional
regulation of vascular
bone morphogenetic protein by
endothelin receptors in early autoimmune diabetes mellitus
Alexander et al., Development 2011
:
Inhibition of
BMP signaling at these stages
reduces expression of the ventral signal
Edn1 , as well as ventral-specific genes such as hand2 and dlx6a in the arches, and expands expression of the dorsal signal jag1b ... Soon after NC migration,
BMP is
required to induce
Edn1 and overexpression of either signal partially rescues ventral skeletal defects in embryos deficient for the other