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IL6 — NAMPT
Text-mined interactions from Literome
Kralisch et al., Am J Physiol Endocrinol Metab 2005
:
Moreover, inhibitor studies suggested that the negative
effect of
IL-6 on
visfatin expression is, at least in part, mediated by p44/42 mitogen activated protein kinase
Moschen et al., J Immunol 2007
(Inflammation...) :
In CD14 ( + ) monocytes,
visfatin induces the production of IL-1beta, TNF-alpha, and especially
IL-6 ... In vivo,
visfatin induces circulating
IL-6 in BALB/c mice
Liu et al., Horm Metab Res 2009
:
Visfatin stimulates production of monocyte chemotactic protein-1 and
interleukin-6 in human vein umbilical endothelial cells ... In summary, these results suggest that
visfatin induced MCP-1 and
IL-6 production involve p38 MAPK, PI3K, and ERK 1/2 pathways in human umbilical vein endothelial cells as determined by inhibition with specific inhibitors
Kim et al., Biochim Biophys Acta 2009
:
Visfatin through STAT3 activation
enhances IL-6 expression that promotes endothelial angiogenesis ... Taken together, our results provide the first example of STAT3 dependent endothelial
IL-6 induction by
visfatin and of the role of IL-6 in mediating visfatin induced angiogenesis
Liu et al., Zhonghua Yi Xue Za Zhi 2009
:
[
Visfatin promotes production of monocyte chemotactic protein-1 and
interleukin-6 in human endothelial cells via insulin receptor ] ...
Visfatin induces endothelial MCP-1 and
IL-6 production in HUVEC in a dose and time-dependently manner
Lappas et al., Mol Cell Endocrinol 2012
:
Visfatin significantly
increased IL-6 and IL-8 gene expression and secretion, COX-2 expression and resultant prostaglandin ( PG ) E ( 2 ) and PGF ( 2a ) release, and 8-isoprostane release