Gene interactions and pathways from curated databases and text-mining

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PBX1 — WNT16

Text-mined interactions from Literome

McWhirter et al., Proc Natl Acad Sci U S A 1999 (Precursor B-Cell Lymphoblastic Leukemia-Lymphoma...) : Inhibition of E2A-Pbx1 expression leads to a significant decrease in WNT-16 mRNA levels, suggesting that WNT-16 is a downstream target of E2A-Pbx1
Casagrande et al., Haematologica 2006 (Precursor B-Cell Lymphoblastic Leukemia-Lymphoma...) : The effects of siRNA mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line ... Targeted-E2A-PBX1 inhibition leads to reduced expression of the EB-1 and Wnt16b genes ; aberrant expression of these genes may be a key step in leukemogenesis in t ( 1 ; 19 ) -positive pre-B leukemia