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NOS3 — PECAM1

Text-mined interactions from Literome

Tai et al., J Biol Chem 2005 : Tie2 and PECAM1 expression decreased > 80 % after siRNA treatment, and flow stimulated phosphorylation of ERK1/2, Akt, and endothelial nitric oxide synthase was significantly inhibited by Tie2 and PECAM1 siRNA
Fleming et al., J Cell Sci 2005 : Role of PECAM-1 in the shear-stress induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells ... Since a major constituent of these endothelial cell-cell contacts is the platelet endothelial cell adhesion molecule-1 ( PECAM-1 ) we assessed the role of PECAM-1 in the activation of eNOS ... Down-regulation of PECAM-1 using a siRNA approach attenuated the shear-stress induced phosphorylation of Akt and eNOS , as well as the shear-stress induced accumulation of cyclic GMP levels while the shear-stress induced phosphorylation of AMPK remained intact
Peterson et al., J Pharmacol Exp Ther 2007 (Body Weight...) : In conclusion, HO-1 and eNOS are relevant targets for D-4F and may contribute to the D-4F mediated increase in TM and CD31 ( + ), the antioxidant and anti-inflammatory properties, and confers robust vascular protection in this animal model of type 1 diabetes
McCormick et al., Arterioscler Thromb Vasc Biol 2011 : The current study was conducted to determine the role of PECAM-1 in the regulation of basal eNOS activity