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IGF1 — SELE

Text-mined interactions from Literome

Hansen et al., J Clin Endocrinol Metab 2004 (Metabolism, Inborn Errors) : Furthermore, we studied the direct effect of GH and IGF-I and serum from GH-treated subjects on basal and TNF alpha stimulated expression of VCAM-1 and E-selectin on cultured human umbilical vein endothelial cells ... In human umbilical vein endothelial cells, there was no direct stimulatory effect of either GH or IGF-I on the expression of VCAM-1 and E-selectin , but serum from GH-treated healthy subjects significantly increased the expression of VCAM-1 ( P < 0.01 )
Bäck et al., J Endocrinol 2012 (Inflammation) : IGF1 stimulated DNA synthesis at 10 ( -8 ) ?mol/l and glucose accumulation at 10 ( -7 ) ?mol/l in HMVEC-Cs. TNF-a dramatically increased E-selectin expression, but no inflammatory or anti-inflammatory effects of insulin, IGF1 or high glucose were seen