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EIF2S1 — IFNG

Text-mined interactions from Literome

Bennett et al., Blood 2006 (Inflammation...) : Thus, knock-down of RAX expression by 80 % using small interfering RNA ( siRNA ) prevents IFNgamma/tumor necrosis factor alpha (TNFalpha) induced PKR activation and eIF2alpha phosphorylation, IkappaB degradation, IRF-1 expression, and STAT1 phosphorylation, resulting in enhanced murine embryonic fibroblast (MEF) cell survival
Hu et al., Am J Physiol Gastrointest Liver Physiol 2010 : The IFN-gamma and TNF-alpha effects in upregulation of stress granule formation and downregulation of Hsp70 were eIF-2alpha dependent , and the effect could be negated by blocking eIF-2alpha phosphorylation with use of an RNA dependent protein kinase inhibitor
Samuel et al., Virology 1983 : However, neither IFN-alpha A nor IFN-gamma induced the phosphorylation of P1 and eIF-2 alpha in GM2767A cells
Koromilas et al., J Biol Chem 1995 (Lymphoma, B-Cell...) : Phosphorylation of eIF-2 alpha was not increased by lipopolysaccharide or IFN-gamma , suggesting that PKR mediates kappa gene transcriptional activation without affecting protein synthesis