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IL8 — STX2

Text-mined interactions from Literome

Zhang et al., Experimental biology and medicine (Maywood, N.J.) 2001 : In contrast to TNF-alpha mRNA, anisodamine at concentrations as high as 400 micrograms/ml did not decrease Stx2 induced IL-1 beta and IL-8 mRNA levels
Zoja et al., Kidney Int 2002 (Hemolytic-Uremic Syndrome) : To obtain more insight into the mechanisms favoring endothelium-leukocyte interaction, we studied ( 1 ) the effect of Stx-2 on leukocyte adhesion and transmigration in human endothelial cells under flow ; ( 2 ) the effect of Stx-2 on endothelial expression of monocyte chemoattractant protein-1 ( MCP-1 ) and interleukin-8 (IL-8) and their functional role in the adhesive phenomena ; and ( 3 ) the role of nuclear factor-kappaB (NF-kappaB) in endothelial chemokine expression ... Stx-2 increased the expression of IL-8 and MCP-1, which was preceded by NF-kappaB activation
Guessous et al., Thromb Haemost 2005 (Leukemia) : Primary human monocytes also released large amounts of IL-8 in response to LPS and Stx2
Jandhyala et al., Cell Microbiol 2008 (MAP Kinase Signaling System) : Treatment of cells with DHP-2 also blocks Stx2/ricin mediated upregulation of the proinflammatory cytokine interleukin-8 and results in a modest but statistically significant improvement in cell viability following Stx2/ricin treatment
Yamasaki et al., FEBS Lett 1999 : IL-8 production at the protein level was enhanced by Stx1 and Stx2 , but not by the mutant Stx1