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IL8 — RBBP7

Text-mined interactions from Literome

Ashburner et al., Mol Cell Biol 2001 : Finally, we show that inhibition of HDAC activity with TSA causes an increase in both basal and TNF induced expression of the NF-kappaB regulated interleukin-8 (IL-8) gene
Rahman et al., Biochem Pharmacol 2002 (Pneumonia) : Pharmacological inhibition of HDAC leads to the increased HAT activity, AP-1 and NF-kappaB activation, and IL-8 release by H2O2 or TNF-alpha treatments
Schmeck et al., J Immunol 2008 : Legionella induced histone modification as well as HAT-/HDAC dependent IL-8 release could also be shown in primary lung epithelial cells
Chavey et al., Mol Pharmacol 2008 (Breast Neoplasms) : Moreover, run-on and transfection experiments demonstrated that IL-8 induction by HDAC inhibitors was transcriptional and involved mainly the nuclear factor-kappaB (NF-kappaB) site of the IL-8 promoter ... In summary, our results demonstrate that NF-kappaB pathway repression by HDAC is responsible for the low expression of IL-8 in ERalpha positive breast cancer cells