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CD4 — TNFSF10
Text-mined interactions from Literome
Tsai et al., Arthritis Rheum 2004
(Lupus Erythematosus, Systemic) :
TRAIL engagement selectively
activated human
CD4 , rather than CD8, T cells and augmented IFNgamma production
Bosque et al., Eur J Immunol 2005
:
Additionally, the inhibition of IL-2 dependent
CD4 ( + ) or CD8 ( + ) T cell blast growth upon CD3 or CD59 ligation was
dependent , at least partially, on FasL and/or
APO2L/TRAIL
Lum et al., AIDS 2005
(HIV Infections) :
The increase in
TRAIL death receptor expression and acquisition of TRAIL sensitivity
requires the chemokine coreceptor CXCR4 but not CCR5 or the
CD4 receptor
Herbeuval et al., AIDS Rev 2006
(HIV Infections) :
However, soluble
CD4 ( sCD4-IgG ) efficiently
blocked IFNalpha production,
TRAIL and DR5 expression and apoptosis of T helper cells
Wang et al., Endocrinology 2009
(Disease Models, Animal...) :
In the present study, we specifically examined
TRAIL effects on
CD4 ( + ) CD25 ( + ) regulatory T cells