Gene interactions and pathways from curated databases and text-mining

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FASN — IGF1

Text-mined interactions from Literome

Stapleton et al., J Biol Chem 1990 : Thus, IGF-1 may play a physiological role in the regulation of hepatic fatty acid synthase during transitions between the starved and fed states, roles previously assigned primarily to insulin and glucagon ... IGF-1 regulates transcription of the fatty acid synthase gene
Porras et al., Mol Endocrinol 1998 : Moreover, transient expression of a transfected active MEK construct ( R4F ) decreased IGF-I induced UCP-1 and insulin induced fatty acid synthase mRNA expression