Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MOK

Text-mined interactions from Literome

Ishihara et al., FEBS Lett 2003 : These data suggest that ERK may play a role in RAGE signaling through direct interaction with RAGE
Cortizo et al., Mol Cell Biochem 2003 : This culture condition also dose-dependently increased the expression of RAGE and the activation of ERK ... These results indicate that, in phenotypically mature osteoblastic cells, changes in ERK activation closely follow the AGEs induced regulation of RAGE expression
Koka et al., Circulation 2006 (Diabetic Angiopathies...) : Furthermore, AGE induced angiotensin II production is blocked by the anti-RAGE antibody and by inhibition of ERK1/2 MAP kinase activities
Ranzato et al., Cell Biochem Biophys 2010 (MAP Kinase Signaling System) : Hmgb1 promotes wound healing of 3T3 mouse fibroblasts via RAGE dependent ERK1/2 activation
Bianchi et al., J Biol Chem 2011 (Encephalitis) : We show here that high S100B stimulates murine microglia migration in Boyden chambers via RAGE dependent activation of Src kinase, Ras, PI3K, MEK/ERK1/2 , RhoA/ROCK, Rac1/JNK/AP-1, Rac1/NF-?B, and, to a lesser extent, p38 MAPK
Li et al., PloS one 2012 (Atherosclerosis...) : RAGE may mediate synergistically increased ERK activation and VSMC proliferation induced by mechanical stretching with and without AGEs