◀ Back to EPHB2
EPHB2 — IL2RA
Text-mined interactions from Literome
Lüschen et al., Biochem Biophys Res Commun 2000
:
Activation of
ERK1/2 and cPLA(2) by the
p55 TNF receptor occurs independently of FAN
Ben-David et al., Scand J Immunol 2007
(Disease Models, Animal...) :
Moreover, inhibition of
ERK1,2 in the dual APL induced regulatory CD4 ( + ) CD25 ( + ) cells,
resulted in downregulation of the forkhead box p3 (Foxp3) gene and protein expression levels, as well as in the downregulation of CD4 ( + )
CD25 ( + ) development, suggesting that the active suppression exerted by the dual APL via CD4 ( + ) CD25 ( + ) cells depends on ERK1,2 activity
Conrad et al., Cell Signal 2009
:
Inhibition of JNK, but not
ERK1/2 or p38 MAPK,
caused a marked reduction in Thy-1 induced
CD25 expression ... In addition, inhibition of p38 MAPK or JNK, but not
ERK1/2 , impaired the growth of IL-2 dependent CTLL-2 T-lymphocytes but did not substantially
affect CD25 expression
Zhao et al., BioMed research international 2013
(MAP Kinase Signaling System) :
Either using PD98059 ( a specific inhibitor for p-ERK ) or depletion of
ERK with small interfering RNA ( siRNA )
reduced the expression of
CD25