Gene interactions and pathways from curated databases and text-mining

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KDR — YES1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: YES1 → KDR (increases, KDR Activity, YES1 Activity) Soldi et al., EMBO J 1999
    Evidence: Through its phosphorylated tyrosine residues, the activated VEGFR-2 associates with the adapter molecules Shc, Grb2 and Nck, to Ras GTPase activating protein, p59fyn, pp62yes and phospholipase Cg, and to the tyrosine phosphatases SHP-1 and SHP-2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *