Gene interactions and pathways from curated databases and text-mining

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NEUROD4 — NEUROG2

Text-mined interactions from Literome

Andersson et al., Exp Cell Res 2007 : We show that over-expression of Ngn2 in these progenitors results in increased neuronal differentiation but does not promote mesDA formation
Gasa et al., Differentiation 2008 : Interestingly, in addition to NeuroD1, Neurog3 also induced both NeuroD2 and NeuroD4 gene expression
Aaker et al., Neurosci Lett 2010 : Ectopic expression analysis showed that MTGR1 and NEUROD4 , which show similar expression patterns, are regulated differently by NEUROG2 and ASCL1
Hindley et al., Development 2012 : Neurogenin 2 (Ngn2) controls neuronal differentiation cell-autonomously by transcriptional activation of targets such as NeuroD, while simultaneously controlling progenitor maintenance non-cell-autonomously by upregulating Delta expression and Notch signalling
Lacomme et al., Mol Cell Biol 2012 : Proneural NEUROG2 ( neurogenin 2 [ Ngn2 ] ) is essential for neuronal commitment, cell cycle withdrawal, and neuronal differentiation
Pan et al., J Biol Chem 2012 : Furthermore, shERK5 attenuates both transcription and neuronal differentiation mediated by Neurogenin 2 , a transcription factor expressed in adult hippocampal neural progenitor cells
Thoma et al., PloS one 2012 : Ngn2 induced neuronal differentiation did not require any additional external or internal factors and occurred even under pluripotency promoting conditions
Guichet et al., Glia 2013 (Brain Neoplasms...) : In the U87 glioma line, Ngn2 could not induce neuronal differentiation although proliferation in vitro and tumoral growth in vivo were strongly reduced