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BMP2 — COL2A1

Pathways - manually collected, often from reviews:

• WikiPathways Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway: COL2A1 → BMP2 (unknown)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: COL2A1 — BMP2 (direct interaction, pull down) Zhu et al., J Cell Biol 1999*
• IRef Biogrid Interaction: COL2A1 — BMP2 (physical association, affinity chromatography technology) Zhu et al., J Cell Biol 1999*
• IRef Hprd Interaction: COL2A1 — BMP2 (in vitro) Zhu et al., J Cell Biol 1999*
• IRef Ophid Interaction: COL2A1 — BMP2 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Mieno et al., J Invest Dermatol 2004 (Hair Diseases...) : Type II collagen accumulation in overlying dermo-epidermal junction of pilomatricoma is mediated by bone morphogenetic protein 2 and 4
Mieno et al., J Cutan Pathol 2005 (Hair Diseases...) : Type II collagen expression in the overlying DEJ and chondroid matrix in CMT may be induced by BMP via the same mechanism as in pilomatricoma
Estes et al., Arthritis Rheum 2006 : Most notably, BMP-6 up-regulated AGC1 and COL2A1 expression by an average of 205-fold and 38-fold, respectively, over day-0 controls, while down regulating COL10A1 expression by approximately 2-fold
Nakanishi et al., Biochem Biophys Res Commun 2009 (Chondromatosis, Synovial) : BMP-2 stimulated the expression of Sox9, Col2a1 , and Aggrecan mRNAs in free-body and synovial cells and that of Runx2, Col1a1, and Osteocalcin mRNAs in the synovial [ corrected ] cells only