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LATS2 — TP53

Text-mined interactions from Literome

Aylon et al., Genes Dev 2006 (Polyploidy) : Lats2 binds Mdm2, inhibits its E3 ligase activity, and activates p53
Finkin et al., Oncogene 2008 (Polyploidy) : Furthermore, Fbw7 expression regulates the p53 dependent induction of genes such as Lats2 and p21 in response to vinblastine
Huang et al., Mol Cell Biol 2009 (Polyploidy) : Phosphorylation at Thr18 enhances p53 dependent activation of not only p21 but also Lats2 , two mediators of the postmitotic checkpoint