Gene interactions and pathways from curated databases and text-mining

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FOXO1 — RALA

Text-mined interactions from Literome

Essers et al., EMBO J 2004 : FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
van den Berg et al., J Biol Chem 2013 : Furthermore, regulation of FOXO by RALA and JIP1 is conserved in C. elegans, where both ral-1 and jip-1 depletion impairs heat shock induced nuclear translocation of the FOXO orthologue DAF16