Itoh et al., Exp Eye Res 2007
:
Constitutively active RhoA increased COL1A2 promoter activity in the presence or absence of TGF-beta2 Ganter et al., Circ Res 2008
(Pulmonary Edema...) :
The results of in vitro studies indicated that IL-1beta caused the activation of transforming growth factor-beta via RhoA/alphavbeta6 integrin dependent mechanisms and the inhibition of the alphavbeta6 integrin and/or transforming growth factor-beta signaling completely blocked the IL-1beta mediated protein permeability across alveolar epithelial cell monolayers