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IFNB1 — IL2RA
Pathways - manually collected, often from reviews:
-
WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway:
CSF3/EPO/IFNA7/CSH1/IFNA7/IFNA7/IFNA7/IFNA7/IFNA7/IFNA7/IFNA7/IFNA7/IFNB1/IL2/OSM/PRL/IFNA7/IFNA7
→
IL3RA/IL2RB/IFNAR1/OSMR/PRLR/IL7R/IL6R/CSF3R/IL2RA/EPOR/IL4R/IL2RG/IFNAR2/GHR
(activation)
Text-mined interactions from Literome
Rep et al., J Neuroimmunol 1996
:
IFN-beta did not inhibit upregulations of CD40L on activated T-cells, but
blocked induction of
CD25 on stimulated T- and B-lymphocytes
Ferrarini et al., J Neuroimmunol 1998
(Multiple Sclerosis) :
Taken all together, our findings suggest that
IFNbeta1b only transiently
affects CD25 expression in vivo, and that this effect can not account for the reported long lasting beneficial action of IFNbeta1b on RRMS