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AHR — IFNG

Text-mined interactions from Literome

Tsitoura et al., J Immunol 2000 (Asthma...) : The protective effect of influenza A on AHR was dependent on IFN-gamma , because protection was abrogated with a neutralizing anti-IFN-gamma mAb
Mehlotra et al., Infect Immun 2001 (Asthma...) : The present study examined the immunomodulatory roles of IL-4 and IFN-gamma in filaria induced AHR and pulmonary inflammation using mice genetically deficient in these cytokines ... These data indicate that IL-4 is required for the induction of filaria induced AHR, whereas IFN-gamma suppresses AHR
Behera et al., Hum Gene Ther 2002 (Asthma...) : Thus, these results demonstrate that mucosal Ad-IFN-gamma gene transfer can effectively attenuate established allergen induced airway inflammation and AHR , predominantly through an IL-12- and STAT4 dependent mechanism
Kumar et al., Inflamm Allergy Drug Targets 2006 (Asthma...) : Treatment with anti-IFN-gamma decreases the number of IFN-gamma producing CD4+ T cells in both wild-type and gene targeted mice, providing a possible explanation for the ability of anti-IFN-gamma to inhibit AHR in the setting of chronic challenge
Neff-LaFord et al., J Immunol 2007 (Orthomyxoviridae Infections...) : We also show that AhR mediated increases in IFN-gamma are dependent upon iNOS, but elevated iNOS in lung epithelial cells is not driven by AhR dependent signals from bone marrow derived cells
Takeda et al., J Immunol 2009 (Asthma...) : Using adoptive transfer experiments, we found that suppression of AHR was mediated by Ag-specific CD8 ( + ) T cells and was dependent on IFN-gamma production by the transferred T cells
Kirstein et al., Infect Immun 2010 (Bronchial Hyperreactivity) : Moreover, depending on the route of sensitization, AHR can be induced either by IL-4/IL-13 or by IFN-gamma