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CDKN1A — DACH1
Text-mined interactions from Literome
Mujoo et al., J Cancer Res Clin Oncol 2003
(Ovarian Neoplasms) :
Wortmannin, a PI3-kinase (PI3-K) inhibitor, caused a dose dependent inhibition of total p53 accumulation, Ser-15 phosphorylation and
p21 ( WAF1/CIP1 ) transactivation in
response to both CDDP and
DACH-Ac-Pt , indicating that members of the PI3-K family are involved in phosphorylation of p53 and that transactivation of p21 ( WAF1/CIP1 ) is p53 dependent
Lee et al., Biochem Biophys Res Commun 2012
(Leukemia, Myeloid) :
Recently we showed that the forced expression of
DACH1 in myeloid cells induced p27 ( Kip1 ) and
repressed p21 ( Cip1 ), which is a pivotal characteristic of the myeloid progenitor