Gene interactions and pathways from curated databases and text-mining

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PLCG2 — RHOA

Text-mined interactions from Literome

Saci et al., Mol Cell 2005 : RhoA is important for BCR dependent synthesis of IP ( 3 ) by PLCgamma2, but is not required for tyrosine phosphorylation of PLCgamma2
Piechulek et al., J Biol Chem 2005 : PLCgamma(2) , but not PLCgamma(1), was markedly activated in intact cells by constitutively active Rac1 ( G12V ), Rac2 ( G12V ), and Rac3 ( G12V ) but not by Cdc42 ( G12V ) and RhoA ( G14V ) ... PLCgamma isozyme-specific activation of PLCgamma(2) by Rac GTPases ( Rac1 approximately Rac2 > Rac3 ), but not by Cdc42 or RhoA , was also observed in a cell-free system