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IL2 — PCNA

Text-mined interactions from Literome

Nelson et al., J Immunol 2003 : IL-2 induces c-myc, cyclin D2, and cyclin E in a redundant manner through the Shc and STAT5 pathways
Kubsch et al., Eur J Immunol 2003 : High levels of the IL-2 dependent cyclin dependent kinase (cdk) inhibitor p27Kip1 were found in anergic CD4+ suppressor T cells resulting in an inhibited activation of retinoblastoma protein and an arrest of cell cycle progression in the G1 phase
Clevenger et al., Endocrinology 1992 : Stimulation of the cloned T cell line L2 with IL2 and PRL induced the sequential expression of interferon regulatory factor-1, c-myc, proliferating cell nuclear antigen , thymidine kinase, cyclin B, and histone H3
Barten et al., Transplant Proc 2005 (Gingival Diseases...) : Compared to CsA therapy, increased TRL concentrations did not further inhibit PCNA expression, inhibited CD25 expression less on days 1 and 2 and equally high on day 3, but inhibited expression of IL-2 and TNF-alpha significantly higher on days 2 and 3 ( P < .05 )
Barten et al., Cell Prolif 2007 : In group II, increased TRL-PK over time did not further inhibit expression of CD25, but inhibited PCNA expression more on day 3, and IL-2 and IFN-gamma expression was significantly higher on days 2 and 3 compared to PD effects of CsA ( P < 0.05 )
Moore et al., J Biol Chem 1987 (Lupus Erythematosus, Systemic) : These data indicate that PCNA/cyclin expression is induced by interleukin 2 and that PCNA/cyclin accumulation is closely associated with T lymphocyte proliferation
Huang et al., Mol Cell Biol 1994 : These results indicate that IL-2 stimulated PCNA transcription may be partially mediated by these CRE binding proteins
Nourse et al., Nature 1994 : During T-cell mitogenesis, antigen-receptor signalling promotes synthesis of cyclin E and its catalytic partner, Cdk2, and interleukin-2 (IL-2) signalling activates cyclin E/Cdk2 complexes
Huang et al., J Biol Chem 1996 : Interleukin 2 (IL-2) stimulates T lymphocyte proliferation and induces the expression of proliferating cell nuclear antigen ( PCNA ), a processivity factor for DNA polymerase delta ... Our results demonstrate that the E2F-like sequence and the protein ( s ) binding to it are required for optimal PCNA promoter activity and IL-2 induction of PCNA expression
Sakaida et al., AIDS Res Hum Retroviruses 1998 : Furthermore, IL-2 dependent kinase activity of the cyclin E-Cdk2 complex was investigated with histone H1 as a substrate