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IL6 — SYT1

Text-mined interactions from Literome

Grassl et al., J Am Soc Nephrol 1999 : Of particular interest was the novel finding of the participation of NF-kappaB p65 in the NF-IL6 complex
Zerbini et al., Cancer Res 2003 (Neoplasms, Hormone-Dependent...) : Our data demonstrate for the first time that a combined aberrant activation of NF-kappaB p50 and p65 and AP-1 JunD and Fra-1 in androgen independent prostate cancer cells results in deregulated IL-6 expression, suggesting a novel potential entry point for therapeutic intervention in prostate cancer
Wang et al., Brain Res 2006 (Reperfusion Injury) : These findings support the hypothesis that upregulation of endogenous retinal IL-6 in retinal I/R injury in microglial/phagocytic cells is controlled predominantly by NF-kappaB p65
Chen et al., J Immunol 2006 : These results suggest that PGN induced IL-6 production involves COX-2 generated PGE ( 2 ), activation of the EP2 and EP4 receptors, cAMP formation, and the activation of PKA, protein kinase C, p38 MAPK, IKKdbeta, kinase alphabeta, p65 phosphorylation, and NF-kappaB
Yoshida et al., Life Sci 2006 : PEDF blocked the IL-6 induced STAT3 phosphorylations and NF-kappaB p65 activity in Hep3B cells
Liu et al., Life Sci 2007 : Other flavonoids, quercetin and cyanidin, which lack alpha, beta unsaturated carbonyl group, showed weaker or no inhibitory effect on both IL-6 induced STAT3 phosphorylation and LPS induced p65 translocation
Butoi et al., Biochim Biophys Acta 2011 : Silencing the p65 ( NF-kB subunit ) inhibited the IL-1ß and IL-6 and silencing c-jun inhibited the TNFa, CX3CR1 and MMP-9 induced by SMC-monocyte interaction
Triñanes et al., Diabetes Care 2012 (Diabetes Mellitus, Type 1) : We evaluated the expression of interleukin (IL)-6 , monocyte chemotractant protein (MCP)-1, vascular cell adhesion molecule (VCAM)-1, intercellular adhesion molecule-1, and the activation of nuclear factor-?ß p65 ( NFkB-p65 )
Ember et al., J Gen Virol 2012 (Poxviridae Infections...) : Consistent with this, C4 inhibited interleukin-1ß induced translocation of p65 into the nucleus
Byun et al., Biochem Biophys Res Commun 2012 (Inflammation) : In addition, EGCG treated DCs inhibited lipopolysaccharide (LPS) induced production of pro-inflammatory cytokines ( tumor necrosis factor [TNF ] -a, interleukin [ IL]-1ß, and IL-6 ) and activation of mitogen activated protein kinases ( MAPKs ), e.g., extracellular signal regulated kinase 1/2 ( ERK1/2 ), p38, c-Jun N-terminal kinase (JNK), and nuclear factor ?B ( NF-?B ) p65 translocation through 67LR
Bruni et al., J Immunol 2013 (Inflammation...) : We show that TBK1 has a positive role in the TLR3-NF-?B pathway, because we detected reduced levels of IL-6 and reduced activation of p65 in TBK1-deficient macrophages
Sancéau et al., J Biol Chem 1995 : Synergistic induction of the IL-6 gene by IFN-gamma and TNF-alpha, in monocytic cells, involved cooperation between the IRF-1 and NF kappa B p65 homodimers with concomitant removal of the negative effect of the retinoblastoma control element present in the IL-6 promoter