Gene interactions and pathways from curated databases and text-mining

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EGFR — NANOG

Text-mined interactions from Literome

Abhold et al., PloS one 2012 (Carcinoma, Squamous Cell...) : Activation of EGFR by the addition of EGF ligand or ectopic expression of EGFR in two established HNSCC cell lines ( UMSCC-22B and HN-1 ) resulted in the induction of CD44, BMI-1, Oct-4, NANOG , CXCR4, and SDF-1
Yi et al., Otol Neurotol 2012 (Neuroma, Acoustic) : Activation of both EGFR and PDGFR resulted in increase in the induction of the expression of the stem cell genes Oct-4 and Nanog and marked increase in tumorsphere forming ability, but only PDGFR activation resulted in an increase in the side population in JS1 cells
Li et al., Journal of translational medicine 2013 : Interestingly, immunofluorescent staining results revealed that increased expression of Nanog and nuclear translocation of ß-catenin occurred concomitantly in response to epidermal growth factor receptor ( EGFR ) signaling in A549 and H23 cells