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EGFR — NANOG
Text-mined interactions from Literome
Abhold et al., PloS one 2012
(Carcinoma, Squamous Cell...) :
Activation of
EGFR by the addition of EGF ligand or ectopic expression of EGFR in two established HNSCC cell lines ( UMSCC-22B and HN-1 )
resulted in the induction of CD44, BMI-1, Oct-4,
NANOG , CXCR4, and SDF-1
Yi et al., Otol Neurotol 2012
(Neuroma, Acoustic) :
Activation of both
EGFR and PDGFR
resulted in increase in the induction of the expression of the stem cell genes Oct-4 and
Nanog and marked increase in tumorsphere forming ability, but only PDGFR activation resulted in an increase in the side population in JS1 cells
Li et al., Journal of translational medicine 2013
:
Interestingly, immunofluorescent staining results revealed that increased expression of
Nanog and nuclear translocation of ß-catenin occurred concomitantly in
response to
epidermal growth factor receptor ( EGFR ) signaling in A549 and H23 cells