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FGF2 — PPARA
Text-mined interactions from Literome
Possati et al., Gen Pharmacol 2000
(Disease Progression...) :
In the presence of
bFGF , on the contrary,
PPAR gamma expression no longer
resulted to a significant association with low incidence of tumor recurrence or progression, suggesting a possible worsening role of this angiogenic factor, typical of papillary cancers, in its interaction with PPAR gamma
Woo et al., Clin Endocrinol (Oxf) 2013
(Metabolic Diseases) :
In the fed state,
FGF21 acts as an autocrine factor in adipocytes,
regulating the activity of
PPAR-? through a feed-forward loop mechanism