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CREB1 — TNF

Text-mined interactions from Literome

Alaaeddine et al., Arthritis Rheum 1999 (Osteoarthritis) : AP-2 and CREB were not induced by TNFalpha
Taylor et al., J Biol Chem 1999 : Furthermore, overexpression of CREB but not mutated CREB by retroviral mediated gene transfer reversed hypoxia elicited induction of TNF-alpha defining a causal relationship between hypoxia elicited CREB reduction and TNF-alpha induction
Delfino et al., J Biol Chem 1999 : Stimulation of Sertoli cells with tumor necrosis factor-alpha , an NF-kappaB activating cytokine produced by round spermatids located adjacent to Sertoli cells, stimulated the elimination of IkappaB, the translocation of additional NF-kappaB to the nucleus, and increased NF-kappaB binding to CREB promoter kappaB enhancer elements ... Tumor necrosis factor-alpha also stimulated transcription from the CREB promoter
Hirota et al., Biochem Biophys Res Commun 2000 : We demonstrated here that intracellular localization of these redox molecules differ from each other and that the redox molecules differentially regulate NF-kappaB, AP-1, and CREB activation induced by TNFalpha , PMA, and forskolin and by expression of signaling intermediate kinases, NIK, MEKK, and PKA in HEK293 cells
Tintut et al., Circulation 2000 (Calcinosis...) : Electrophoretic mobility shift assay demonstrated that TNF-alpha enhanced DNA binding of osteoblast specific factor ( Osf2 ), AP1, and CREB , transcription factors that are important for osteoblastic differentiation
Lee et al., Br J Pharmacol 2003 : The effects of sauchinone on the inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-alpha) and cyclooxygenase 2 (COX-2) gene expression and on the activation of transcription factors, nuclear factor-kappaB (NF-kappaB), CCAAT/enhancer binding protein (C/EBP), activator protein-1 (AP-1) and cAMP-response element binding protein ( CREB ) were determined in Raw264.7 cells as part of the studies on its anti-inflammatory effects
Gustin et al., Am J Physiol Cell Physiol 2004 (MAP Kinase Signaling System) : Dominant negative CREB, an antagonist antibody directed against the type 1 TNF receptor, or pharmacological inhibition of p38 MAPK signaling blocked TNF induced CREB activation as determined by phosphorylation and gene reporter assays
Zhao et al., J Neurosci 2004 (Calcium Signaling) : Using CREB antisense to determine the causal relationship between V1 agonist induced CREB activation and suppression of IL-1beta and TNF-alpha, we demonstrated that decreased IL-1beta and TNF-alpha gene expression was dependent on upstream CREB activation
Ono et al., Arterioscler Thromb Vasc Biol 2004 (MAP Kinase Signaling System) : TNF-alpha induced CREB phosphorylation with a peak at 15 minutes of stimulation ... Pharmacological inhibition of p38 mitogen activated protein kinase ( p38-MAPK ) inhibited TNF-alpha induced CREB phosphorylation ... Adenovirus mediated overexpression of dominant negative form of CREB suppressed TNF-alpha induced CREB phosphorylation and c-fos mRNA expression ... TNF-alpha , a potent migration factor for VSMCs, activated CREB through p38 mitogen activated protein kinase ( p38-MAPK )
Roach et al., Infect Immun 2005 : Our studies are the first to demonstrate an important role for the transcription factor CREB in TNF-alpha production by mycobacterium infected macrophages, as well as a role for M. avium 's induction of PP2A phosphatase activity as a mechanism to limit macrophage activation
Arai et al., Endocrine 2005 (Leydig Cell Tumor...) : TNF did not affect levels of either CREB or phospho-CREB in whole cell lysates ; however, TNF decreased both CREB and phospho-CREB in nuclear extracts in a time dependent manner
Ulfhammer et al., Journal of thrombosis and haemostasis : JTH 2006 (Cardiovascular Diseases...) : Further, we provide evidence for a TNF-alpha induced binding of NF-kappaB to the recently described kappaB site in the t-PA gene and of cyclic adenosine monophosphate response element binding protein ( CREB ) to the t-PA CRE-like site
Adiseshaiah et al., J Immunol 2006 (MAP Kinase Signaling System) : Our findings collectively indicate that ERK signaling plays key roles in both Elk1, CREB , and ATF-1 activation and the subsequent recruitment of c-Jun to the FRA-1 promoter in response to TNF-alpha in pulmonary epithelial cells
Venkatachalam et al., J Biol Chem 2009 (Myocardial Infarction) : TNF-alpha induced CREB phosphorylation in vitro and DNA binding and reporter gene activities in vivo
Mazzone et al., Biosci Trends 2009 (Atherosclerosis) : The failure of UCB to alter TNFalpha induced phosphorylation of cAMP-response element binding protein ( CREB ) suggested that the CREB pathway is not involved in the UCB inhibition and that UCB blunting effect on the overexpression of adhesion molecules occurs via inhibition of the NF-kappaB transduction pathway