Gene interactions and pathways from curated databases and text-mining

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CLDN1 — TNF

Text-mined interactions from Literome

Kondo et al., Int J Mol Med 2008 (Neoplasm Invasiveness...) : Claudin-1 expression is induced by tumor necrosis factor-alpha in human pancreatic cancer cells ... Expression of claudin-1 was up-regulated by TNF-alpha in a concentration dependent manner in PANC-1 cells
Fischer et al., Am J Physiol Gastrointest Liver Physiol 2013 : In addition, TNF-a induced a downregulation of claudin-1 , claudin-2, claudin-4, and occludin as well as activation of phosphatidylinositol 3-kinase signaling in T-84 but not Caco-2 cells, which was reversed by adalimumab