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CD14 — IL3

Text-mined interactions from Literome

Iwagaki et al., Infect Immun 2000 : The purpose of this study was to compare and contrast the endotoxin neutralizing activities of two synthetic antiendotoxin peptides ( SAEP-2 and SAEP-4 ), PMB, and an LPS core-specific monoclonal antibody ( MAb ), WN1 222-5, based on their abilities to inhibit CD14 mediated target cell uptake of fluorescein isothiocyanate ( FITC ) -conjugated LPS, detected by flow cytometry and confocal microscopy, and LPS induced production of the proinflammatory cytokines, interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha), as measured by bioassays
Takamatsu et al., J Immunol 1996 : Granulocyte/macrophage CSF (GM-CSF) or IL-3 strongly enhanced LPS induced histamine formation and expression of CD14 on bone marrow derived macrophages, without affecting the expression of Mac-1 Ag ... In contrast to these cytokines, IFN-gamma suppressed LPS induced histamine production regardless of whether it was stimulated by GM-CSF or IL-3 , and inhibited CD14 expression