Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
PIP5K1C
→
RAC1
(increases, PIP5K1C Activity)
Evidence: Studies in human T cells show that both RAC1 and RHOA are required to transduce chemokine receptor signals to the activation of LFA1 by phospholipase D and PIP5K1gamma106 (Fig. 5).