Gene interactions and pathways from curated databases and text-mining

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ACE — RAC1

Text-mined interactions from Literome

Iwashima et al., Endocrinology 2008 : Dominant negative Rac1 also inhibited aldosterone induced ACE gene expression
Catravas et al., Br J Pharmacol 1990 : 4. When the single pass transpulmonary binding of 80pmol [ 3H ] -RAC-X-65 ( an ACE inhibitor ) was measured in additional rabbits, a significant ( P < 0.05 ) decrease in RAC-X-65 binding was observed 30s after captopril ( 80 % decrease ) or CL242,817 ( 85 % decrease ), a result expected for a loss of catalytically active enzyme mass due to tightly bound captopril or CL242,817