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NPPA — TGFB2

Text-mined interactions from Literome

Nishikimi et al., J Hypertens 2004 (Glomerulosclerosis, Focal Segmental...) : After 7 weeks, untreated DS were characterized by decreased kidney function, increased proteinuria, abnormal morphological findings, increased adrenomedullin and atrial natriuretic peptide (ANP) levels, and increased renal messenger RNA expression of RhoB, Rho-kinasealpha, Rho-kinasebeta, collagen I and collagen III, and transforming growth factor-beta ( TGF-beta ) in the renal cortex compared with DR. Chronic fasudil treatment significantly improved renal function ( serum creatinine, -26 % ; blood urea nitrogen, -41 % ; creatinine clearance, +42 % ), proteinuria ( -24 % ) and histological findings ( glomerular injury score, -49 % ; afferent arteriolar injury score, -17 % ) without changing blood pressure compared with untreated DS
Wolf et al., J Am Soc Nephrol 1995 : This study examined the effects of ANP on the expression and synthesis of transforming growth factor-beta ( TGF-beta ) in a cultured murine mesangial cell line ( MMC )