Gene interactions and pathways from curated databases and text-mining

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CRK — PPARG

Text-mined interactions from Literome

Uchimura et al., Hepatology 2001 : PPAR gamma:RXR activation did not affect the level of LPS induced phosphorylation of c-jun N-terminal kinase and p38 mitogen activated protein kinase
Schild et al., Placenta 2006 : Whereas PPARgamma did not alter p38 expression, p38 inhibitors diminished the transcriptional activity of PPARgamma in primary trophoblasts ... Our data support an effect of p38 on PPARgamma protein stability because p38 inhibition led to reduced expression of PPARgamma protein without a significant effect on PPARgamma mRNA, and this reduction was blocked by the protease inhibitor MG-132
Zheng et al., Biol Chem 2007 : SB203580, a p38MAPK inhibitor, was able to inhibit the phosphorylation of p38MAPK , but did not reduce the expression of PPARgamma2
Dai et al., J Dermatol Sci 2008 : Moreover, dn-PPAR gamma prevented the 1 alpha,25 ( OH ) 2D3 induced phosphorylation of p38 ... These results suggest that PPAR gamma regulates involucrin expression by controlling the AP-1 signal and p38 activation in 1 alpha,25 ( OH ) 2D3 induced keratinocyte differentiation