◀ Back to TGFB1
PIP — TGFB1
Text-mined interactions from Literome
Jung et al., J Am Soc Nephrol 2007
:
Thus,
TGF-beta1 regulates the
PIP complex in a cell type dependent manner ... Because the PIP complex promotes glomerular mesangial matrix deposition and protects podocytes from apoptosis, the
TGF-beta1 induced up- and downregulation of the
PIP complex likely contribute to the pleiotropic effects of TGF-beta1 on different glomerular cell types and hence the progression of glomerular failure
Kim et al., Exp Mol Med 2007
:
The
TGF-beta1 induced up- and down-regulation of the
PIP complex formation likely contributes to the pleiotropic effects of TGF-beta1 on mesangial cell proliferation and hypertrophy through cellular localization of p27 ( Kip1 ) and alteration of Akt and p38 phosphorylation