Gene interactions and pathways from curated databases and text-mining

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PIP — TGFB1

Text-mined interactions from Literome

Jung et al., J Am Soc Nephrol 2007 : Thus, TGF-beta1 regulates the PIP complex in a cell type dependent manner ... Because the PIP complex promotes glomerular mesangial matrix deposition and protects podocytes from apoptosis, the TGF-beta1 induced up- and downregulation of the PIP complex likely contribute to the pleiotropic effects of TGF-beta1 on different glomerular cell types and hence the progression of glomerular failure
Kim et al., Exp Mol Med 2007 : The TGF-beta1 induced up- and down-regulation of the PIP complex formation likely contributes to the pleiotropic effects of TGF-beta1 on mesangial cell proliferation and hypertrophy through cellular localization of p27 ( Kip1 ) and alteration of Akt and p38 phosphorylation