Mei et al., PloS one 2011
:
While BDNF did not alter the steady-state level of PKM?, BDNF together with the L-LTP inducing theta-burst stimulation (TBS) increased PKM? level even without protein synthesis
Melemedjian et al., Molecular pain 2013
(Chronic Pain...) :
Here we have tested the hypothesis that brain derived neurotrophic factor (BDNF) regulates PKM? , and possibly other aPKCs, to maintain a centralized chronic pain state ... Moreover, at spinal synapses, BDNF controls PKM? and PKC? nascent synthesis via mTORC1 and BDNF enhances PKM? phosphorylaton