Gene interactions and pathways from curated databases and text-mining

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MMP2 — NRAS

Text-mined interactions from Literome

Thant et al., Oncogene 1999 (Neoplasm Invasiveness) : In SR3Y1 clones transfected with S17N ras, augmented secretion and proteolytic activation of MMP-2 were dramatically suppressed by S17N Ras expression, while tyrosine phosphorylation of cellular proteins was not suppressed
Song et al., Cancer Res 2006 (Breast Neoplasms...) : We showed previously that H-Ras, but not N-Ras , induced invasion of MCF10A human breast epithelial cells through Rac-MKK3/6-p38 pathway resulted in MMP-2 up-regulation
Kim et al., J Biochem Mol Biol 2007 : Type I collagen induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells ... The present study investigated if H-Ras and/or N-Ras induces pro-MMP-2 activation of MCF10A cells when cultured in two-dimensional gel of type I collagen