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MMP2 — NRAS
Text-mined interactions from Literome
Thant et al., Oncogene 1999
(Neoplasm Invasiveness) :
In SR3Y1 clones transfected with S17N ras, augmented secretion and proteolytic activation of
MMP-2 were dramatically
suppressed by
S17N Ras expression, while tyrosine phosphorylation of cellular proteins was not suppressed
Song et al., Cancer Res 2006
(Breast Neoplasms...) :
We showed previously that H-Ras, but not
N-Ras , induced invasion of MCF10A human breast epithelial cells through Rac-MKK3/6-p38 pathway
resulted in
MMP-2 up-regulation
Kim et al., J Biochem Mol Biol 2007
:
Type I collagen induced
pro-MMP-2 activation is differentially
regulated by H-Ras and
N-Ras in human breast epithelial cells ... The present study investigated if H-Ras and/or
N-Ras induces
pro-MMP-2 activation of MCF10A cells when cultured in two-dimensional gel of type I collagen