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IL4 — PTHLH

Text-mined interactions from Literome

Funk et al., Endocrinology 1994 : IL-4 , a prototypical antiinflammatory cytokine, also had a paradoxical effect on LPS induction of splenic PTHrP mRNA levels ... Instead of inhibiting LPS induction of splenic PTHrP mRNA levels in OuJ or HeJ mice, IL-4 ( 200 ng ) actually stimulated PTHrP mRNA levels
Ikeda et al., Endocrinology 1993 (Deltaretrovirus Infections...) : The secretion of PTHRP , as determined by both a newly established immunoradiometric assay using recombinant human PTHRP ( 1-87 ) as the standard and an RIA using an antibody against PTHRP ( 109-141 ), was increased by IL-2 but not by IL-1, IL-3, IL-4 , or IL-6
Casey et al., J Clin Endocrinol Metab 1993 : 17 beta-Estradiol ( E2 ), interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF alpha), endothelin-1 (ET-1), transforming growth factor-beta 1 ( TGF beta 1 ), and serum stimulated PTH-rP production ( evaluated by immunoassay of PTH-rP in the culture medium ) by these cells
Mori et al., Jpn J Cancer Res 1993 (Leukemia, T-Cell) : To elucidate whether PTHrP produced by ATL cells is regulated by IL-2 or IL-4 , we investigated the in vitro effects of IL-2 and IL-4 on the release of PTHrP ... IL-2 increased the release of PTHrP into the conditioned medium from leukemic cells in some, but not all, ATL patients ; however, IL-4 did not affect the PTHrP release