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MMP9 — TAT

Text-mined interactions from Literome

Kumar et al., FEBS Lett 1999 : In the present report, we demonstrate that HIV-tat induced expression of MMP-9 is blocked by inhibitors of protein tyrosine phosphatases ( PTPases )
Nyberg et al., J Dent Res 2002 (Carcinoma, Squamous Cell...) : The TAT-2 overexpression significantly increased the levels of active MMP-9 in the most malignant cell line
Ju et al., Exp Mol Med 2009 (AIDS Dementia Complex...) : In this study, we examined the effect of HIV-1 Tat on the expression of MMP-9 in CRT-MG human astroglioma cells ... Pretreatment of CRT-MG cells with MAPK inhibitors suppressed Tat induced MMP-9 expression ... Furthermore, HIV-1 Tat induced expression of MMP-9 was significantly inhibited by neutralization of TNF-alpha, but not IL-1beta and IL-6
Song et al., BMB Rep 2011 : In addition, Tat-SOD suppressed TNF-a induced gelatinolytic activity of MMP-9 ... Taken together, our results indicate that Tat-SOD can suppress TNF-a induced MMP-9 expression via ROS-NF-?B dependent mechanisms in keratinocytes, and therefore can be used as an immunomodulatory agent against inflammatory skin diseases related to oxidative stress
Lecoeur et al., Cell death & disease 2012 : The anion-channel inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid ( DIDS ) protects isolated mitochondria against Tat induced mitochondrial membrane permeabilization ( MMP ) , whereas ruthenium red, a ryanodine receptor blocker, does not ... Pharmacologic inhibitors of the permeability transition pore, Bax/Bak inhibitors, and recombinant Bcl-2 and Bcl-XL proteins do not reduce Tat induced MMP