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CYP19A1 — IL1B

Text-mined interactions from Literome

Shozu et al., J Clin Endocrinol Metab 2001 (Leiomyoma...) : On the other hand, 8-d treatment with leuprorelin acetate ( 100 nmol/liter ) reduced dexamethasone + IL-1beta induced activity and a mRNA level of aromatase by 28 % and 42 %, respectively
Shozu et al., J Steroid Biochem Mol Biol 2001 : PD98059 ( 100 microM ) reduced DEX+interleukin (IL)-1beta induced aromatase activity in human osteoblast-like cells by more than 90 %, whereas 50 % of the aromatase mRNA concentration was retained compared with the control incubated with DEX+IL-1beta
Ma et al., Zhonghua Fu Chan Ke Za Zhi 2002 : [ Effect of interleukin-1beta on aromatase activity in human osteoblast-like cells ] ... In the present study, the effect of IL-1beta and IL-1ra on aromatase (Arom) activity and mRNA expression in human osteoblast-like cells was investigated by [ ( 3 ) H ] water released upon the conversion of [ 1beta- ( 3 ) H ] androstenedione to estrone and the reverse-transcription polymerase cain reaction ( RT-PCR ) method
Takemura et al., J Clin Endocrinol Metab 2007 (Endometriosis...) : Metformin suppresses interleukin (IL)-1beta induced IL-8 production, aromatase activation , and proliferation of endometriotic stromal cells ... Metformin dose-dependently suppressed IL-1beta induced IL-8 production, cAMP induced mRNA expression and aromatase activity, and 5-bromo-2'-deoxyuridine incorporation in ESCs
Gottschall et al., J Reprod Immunol 1989 : These results suggest that IL-1 beta may play some role in the multifactorial regulation of aromatase and estrogen secretion in the early developing follicle, and IL-1 beta may exert an effect on the cAMP-adenylate cyclase messenger system in granulosa cells
Nestler et al., Endocrinology 1993 : In time-course studies, significant stimulation of the conversion of androstenedione to estrogens by hIL-1 beta could be detected as early as after 4 h of treatment and persisted for at least 24 h. Human IL-1 alpha stimulated the conversion of androstenedione to estrogens to an extent similar to that of hIL-1 beta, whereas the effects of murine IL-1 beta on aromatase activity were inconsistent
Hughes et al., Int J Cancer 1996 (Breast Neoplasms) : Regulation of arachidonic acid metabolism, aromatase activity and growth in human breast cancer cells by interleukin-1beta and phorbol ester : dissociation of a mediatory role for prostaglandin E2 in the autocrine control of cell function ... While indomethacin had no effect on induction of aromatase activity by IL-1beta and TPA, dexamethasone exhibited a temporally biphasic action ... Dexamethasone alone stimulated aromatase activity and demonstrated a permissive action on aromatase stimulation by IL-1beta and TPA ... However, pre-treatment of cells with dexamethasone prevented subsequent induction of aromatase activity by IL-1beta and TPA ... We conclude that the cyclooxygenase pathway does not play a mediatory role during the inhibition of cell growth and the induction of aromatase activity by IL-1beta and TPA
Noble et al., J Clin Endocrinol Metab 1997 (Endometriosis...) : The effects of interleukin-1 beta (IL-1 beta) , IL-2, IL-6, IL-11, oncostatin M, IL-15, tumor necrosis factor-alpha, PGE2, estradiol, R5020, dexamethasone, and dibutyryl cAMP ( Bt2cAMP ) on aromatase activity in endometriosis derived stromal cells were assessed